Tuesday, August 25, 2020
antigun control essays
antigun control papers I. Intro. - Imagine you are sitting home one night with nothing to do. Your folks have left for the end of the week and there is definitely nobody around. So you lounge around that late evening sitting in front of the TV for some time yet discover nothing on worth viewing. You go on upstairs to your room and prepare for bed. Mood killer the lights, set down, and close your eyes. Out of nowhere you here an accident of glass in your kitchen. You hurry to your feet and put your ear to the entryway tuning in to whats going on ground floor. You start to hear the voice of two men as they begin experiencing the parlor, advancing toward the steps, directly outside your room. What do you do? You arent going to stand up to them since its equitable you-recollect you thought you heard two of them right? Well you are truly stuck in your room and everything you can do is stay there trusting that they leave soon and dont hurt you. Presently on the off chance that it were at my home things would be somewhat extraordinary. First off I would get out my shotgun from my storage room and start to perceive what is gin on down steps. When those criminals saw me strolling around with a weapon, you better accept they would mull over staying any more. A. 39% of criminals prematurely ended a wrongdoing because of the casualty being furnished B. 74% state they maintained a strategic distance from residences all together in the event that they believed they may be shot. One of the significant contentions against the hypothesis that weapon control would spare lives is that albeit 66% of all manslaughters are submitted with guns, gun controls would have no impact on crime, since human instinct is the thing that it is. Regardless of whether weapons vanished from the wrongdoing scene, hoodlums would supplant them with blades, clubs, tomahawks, or even clench hands. Weapons dont execute individuals, individuals slaughter individuals. Expressed essentially, these wrongdoings happen in light of the fact that a few people have come to abhor others, and they will keep on happening in some structure as long a ... <!
Saturday, August 22, 2020
The eNotes Blog Does AP stand for Absolutely Pointless
Does AP represent Absolutely Pointless My 12-year-old child started his first semester in middle school this year. In July, we all guardians were gathered together for a three-hour data class. We visited every one of the Pre-AP educators rooms, à a aggregate of seven diverse potential course contributions. In each meeting, the message was the equivalent: you selected your child in ALL Pre-AP classes if your kid isnt a total sham. Pre-AP, it was (here and there not) calmly clarified, was vital for your youngster with the goal that the individual in question could take AP courses in secondary school, and afterward be qualified to skirt starting courses in school. The point, obviously, was to set aside us a little cash and to (it was suggested) feel somewhat predominant about our posterity. Similar instructors who educate Pre-AP classes additionally show normal courses. Despite the fact that our data course should disclose to us the distinction between the two sorts of classes, for all intents and purposes none à of the instructors even referenced the normal classes. The Pre-AP was pushed so hard it caused a parent to feel like conceding your child was as on par mentally with the Honey Boo faction for basically getting some information about the distinctions. As the night rambled endlessly, I started to ponder: Whatever happened to training understudies at the genuine level they are at, mentally, inwardly, and socially? I pondered as well, as a school educator myself, if AP is pushed so vigorously, can any anyone explain why I discover my rookies so not ready for the rigors of a school course?à This week, the Atlanticâ published an article by John Tierney, a resigned educator and secondary school AP instructor. Like me, Tierney pondered something very similar. So why this tremendous drive into AP? à Probably the most compelling motivation is that the College Board, which sets the gauges and distributes the AP educational plan, acquires over portion of its income from AP courses. Which may be okay with everybody if secondary schools genuinely were turning out improved and propelled students. Be that as it may, in Tierneys experience, and my own, they are not doing any such thing. Tierney examined the numerous purposes behind the disappointments of the AP projects, and some disarray about their guarantees. For example,â while AP courses in secondary school may let a school first year recruit quit a starting course, they frequently don't get genuine school acknowledge for AP classes true to form. What's more, when they do get the opportunity to skirt an introduction class, numerous understudies find that their AP classes in secondary school don't remotely take after the difficulties of a genuine school class, and many wish they HAD taken the customary early on school course. Another substantial contention is Tierneys resistance to open enlistment for à AP classes. à This was the situation in my children new school. There was no legitimacy base. à No one was solicited to join on the grounds that from high scores in primary school or an educators proposal. What we were fundamentally told is that Pre-AP was do or die. Tierney contends that, 66% of the understudies taking my class every year didn't have a place there. Also, they hauled down the course for the understudies who did. What's more, what of the children who neglect to swim? Its entirely troubling, as per Tierney. He says that those classes get always full as the years wear on and a few children simply cant hack it, however they are not given the most grounded educators. Those educators, obviously, are saved for the AP program. A great deal of these non-swimmers are minorities, who will presently confront much more impediments to advanced education. At last, and fortifying what I have just found in my own home, the push to cover so much material so quick prompts unbending stultification a sort of careless genuflection to an endorsed arrangement of study that crushes innovativeness and free request. No big surprise when I took my Freshmen out on a radiant day and we as a whole sat idle however read Thoreau for all to hear to each other, they all looked paralyzed then they gradually started to unwind, grin, and appreciate the joys of learning. Tragically, secondary teachers can't bring their understudies down fascinating ways of learning. After all theres a test coming up.
Wednesday, August 5, 2020
Hearing Girls Non-Fiction About Girls, Women, and Feminism
Hearing Girls Non-Fiction About Girls, Women, and Feminism When Im not reading YA fiction, Im consuming non-fiction, especially of the pop psychology or sociology variety. What tends to check all my boxes with non-fiction is what falls into the category of work about girls and women. Some of it is explicitly feminist in leaning and others are not, despite discussing the very things feminists care about. Some of it follows a narrative while others tend to fall into the essay category a realm of writing I not only love but that I think women are able to really find and share their voices. I dont believe you have to agree with everything in a non-fiction book for it to be good. In fact, I think a non-fiction book can become really good for me when I find myself disagreeing with many points; the more my mind wants to think about things, the more Im interacting with the book. Books that last the longest for me are the ones that have some sort of intellectual or emotional impact. Heres a look at a handful of recent and forthcoming books that fall squarely into the category of non-fiction about girls, women, and feminism worth checking out. Ive read each of these and recommend them for the thought fodder, even though I wouldnt say I agree with everything they each say. Im a firm believer than teenagers are able to read what interests them in adult non-fiction when theyre ready to do so, same as they would with fiction, so the books here which arent marketed for YA would still be perfectly suitable for teens who have an interest. I have a feeling, perhaps from experience, that many teen girls are interested in reading work thats focused exclusively on them or about them in a way where their voices are the ones being discussed. These descriptions come from Goodreads, so its worth noting theres a bit of sensationalism with a few of them. Im always a bit surprised to see how copy to describe a book can twist whats going on with the book in ways that seem to disagree with what the books actually saying. In books like these, theres sometimes an inadvertent blame/causation placed upon girls for behavior, rather than the bigger issue of social or cultural politics. Id love any recommendations from others of books on similar themes and topics, especially as they relate to girls and women of color. Its worth noting that the two essay collections in here share voices of women of color, and the two research-based books make clear their research involved voices from girls of color (and they acknowledge where their blindspots are, which I think is as important). American Girls: Social Media and The Secret Lives of Teenagers by Nancy Jo Sales (Knopf, February 23) With extraordinary intimacy and precision, Sales captures what it feels like to be a girl in America today. From Montclair to Manhattan and Los Angeles, from Florida and Arizona to Texas and Kentucky, Sales crisscrossed the country, speaking to more than two hundred girls, ages thirteen to nineteen, and documenting a massive change in the way girls are growing up, a phenomenon that transcends race, geography, and household income. American Girls provides a disturbing portrait of the end of childhood as we know it and of the inexorable and ubiquitous experience of a new kind of adolescenceâ"one dominated by new social and sexual norms, where a girlâs first crushes and experiences of longing and romance occur in an accelerated electronic environment; where issues of identity and self-esteem are magnified and transformed by social platforms that provide instantaneous judgment. What does it mean to be a girl in America in 2016? It means coming of age online in a hypersexualized cul ture that has normalized extreme behavior, from pornography to the casual exchange of nude photographs; a culture rife with a virulent new strain of sexism and a sometimes self-undermining notion of feminist empowerment; a culture in which teenagers are spending so much time on technology and social media that they are not developing basic communication skills. From beauty gurus to slut-shaming to a disconcerting trend of exhibitionism, Nancy Jo Sales provides a shocking window into the troubling world of todayâs teenage girls. Girls and Sex: Navigating the Complicated New Landscape by Peggy Orenstein (Harper, March 1) With casual hookups and campus rape relentlessly in the news, parents can be forgiven for feeling anxious about their young daughters. Theyâre also fearful about opening up dialog. Not Orenstein. A contributing writer to the New York Times Magazine and the New York Times best-selling author of books like Cinderella Ate My Daughter, Orenstein spoke to psychologists, academics, and other experts in the field and, yes, 70 young women to offer an in-depth pictures of âgirls and sexâ today. The V-Word: True Stories About First-Time Sex edited by Amber J. Keyser An honest and poignant collection of essays by women about losing their virginity in their teens. The V-Word captures the complexity of this important life-decision and reflects diverse real-world experiences. Includes helpful resources for parents and teens. Losing it. Popping your cherry. Handing in your V-card. First time sex is a big unknown. Will it be candlelight and rose petals or quick and uncomfortable? Is it about love or about lust? Deciding to have sex for the first time is a choice that#8217;s often fraught with anxiety and joy. But do you have anyone telling you what sex is really like? In The V-Word seventeen writers (including Christa Desir, Justina Ireland, Sara Ryan, Carrie Mesrobian, Erica Lorraine Scheidt, and Jamia Wilson) pull back the sheets and tell all, covering everything from straight sex to queer sex, diving-in versus waiting, and even the exhilaration and disappointment that blankets it all. Some of their experiences happened too soon, some at just the right time, but all paint a broad picture of what first-time sex is really like. Funny, hot, meaningful, cringe-worthy, gross, forgettable, magnificent, empowering, and transformative, the stories in The V-Word are never preachy, but provide a map for teens to chart their own course through the steamy waters of sex. (Full disclosure: I am one of the seventeen writers included in this collection but Ive read this cover-to-cover and think it is invaluable). You Dont Have To Like Me: Essays on Growing Up, Speaking Out, and Finding Feminism by Alida Nugent Nugent is a proud feministâ"and sheâs not afraid to say it. From the âscarlet Fâ thrust upon you if you declare yourself a feminist at a party to how to handle judgmental store clerks when you buy Plan B, You Donât Have to Like Me skewers a range of cultural issues, and confirms Nugent as a star on the rise. This book hit my mailbox recently and though I havent read it yet, it sounds absolutely like it fits my reading interests to a T. Ive heard Hurley speak before and know she shares a language with me on a number of topics. The Geek Feminist Revolution by Kameron Hurley (Tor, May 31) The Geek Feminist Revolution is a collection of essays by double Hugo Award-winning essayist and science fiction and fantasy novelist Kameron Hurley. The book collects dozens of Hurleyâs essays on feminism, geek culture, and her experiences and insights as a genre writer, including âWe Have Always Fought,â which won the 2014 Hugo for Best Related Work. The Geek Feminist Revolution will also feature several entirely new essays written specifically for this volume. I picked this book up recently but havent gotten to it yet, in part because its got the same title as a YA novel I just finishedwhich tackled a very similar topic. Asking For It: The Alarming Rise of Rape Culture and What We Can Do About It by Kate Harding Dominique Strauss-Kahnâs arrest. Congressman Todd Akinâs âlegitimateâ gaffe. The alleged rape crew of Steubenville, Ohio. Sexual violence has been so prominent in recent years that the feminist term ârape cultureâ has finally entered the mainstream. But what, exactly, is it? And how do we change it? In Asking for It, Kate Harding answers those questions in the same blunt, bullshit-free voice thatâs made her a powerhouse feminist blogger. Combining in-depth research with practical knowledge, Asking for It makes the case that twenty-first century Americaâ"where itâs estimated that out of every 100 rapes only 5 result in felony convictionsâ"supports rapists more effectively than victims. Harding offers ideas and suggestions for addressing how we as a culture can take rape much more seriously without compromising the rights of the accused. And finally, I am waiting anxiously to get my hands on a copy of this. Knowing Wests voice and perspective, I suspect its going to be outstanding: Shrill: Women Are Funny, Its Okay To Be Fat, and Feminists Dont Have To Be Niceby Lindy West (Hachette, May 19) Lindy West is ferociously witty and outspoken, tackling topics as varied as pop culture, social justice and body image. Her empowering work has garnered a coast-to-coast audience that eagerly awaits SHRILL, her highly-anticipated literary debut. West has rocked readers in work published everywhere from The Guardian to GQ to This American Life. She is a catalyst for a national conversation in a world where not all stories are created equal and not every body is treated with equal respect. SHRILL is comprised of a series of essays that bravely shares her life, including her transition from quiet to feminist-out-loud, coming of age in a popular culture that is hostile to women (especially fat, funny women) and how keeping quiet is not an option for any of us. Sign up for True Story to receive nonfiction news, new releases, and must-read forthcoming titles. Thank you for signing up! Keep an eye on your inbox.
Saturday, May 23, 2020
Monday, May 11, 2020
Franz Kafka s Metamorphosis An Interpretation - 958 Words
Franz Kafkaââ¬â¢s ââ¬Å"Metamorphosisâ⬠: An Interpretation The very first line of one of the most famous novellas of the 20th century, Franz Kafkaââ¬â¢s Metamorphosis, is puzzling. It tells us that the main character awakes one day and finds himself turned into ââ¬Å"ungeheueren Ungezieferâ⬠(Gooderham par. 4). It has proven difficult to translate the line into English, as there is no precise translation. Meaning some ââ¬Å"enormous or monstrous kind of unclean verminâ⬠(Gooderham par. 7), it denotes ââ¬Å"something nasty, but not specificâ⬠(Robertson 2:31). The meaning of the whole story remains similarly uncertain, and numerous readings of it have emerged in literary criticism. In our paper, we will make an attempt to give a possible interpretation of the novella, supporting it with some arguments, and then we will discuss the storyââ¬â¢s ambiguity further. In our opinion, ââ¬Å"Metamorphosisâ⬠can be understood as a metaphor for the great weakness and disease of the elderly. Only here, the disease comes suddenly and harshly, and all the changes following it are also rapid, much stronger and more obvious. When Gregor turns into the creature, his family quickly forgets about all the good he has done. They lock him in his room, and all of his human features are forgotten. The only person who visits the protagonist is his younger sister, who has accepted the responsibility of cleaning up after him and feeding him. She does her chore quickly, feeling disgusted. Gregorââ¬â¢s family mainly sees him as a useless andShow MoreRelatedThe True Metamorphosis.. Franz Kafka Owns A Part Of The1448 Words à |à 6 PagesThe True Metamorphosis. Franz Kafka owns a part of the human emotional spectrum, which the world can now call the Kafkaesque, a term for someone who exhibits nightmarish qualities of Kafkaââ¬â¢s fictional world (Franz Kafka). Kafkaââ¬â¢s twisted world is in no way pleasant, very Kafkaesque. It feels like a nightmare, and yet it is a place where many people, if only for a moment, will end up. Kafkaââ¬â¢s most appreciated piece of literature, ââ¬Å"The Metamorphosis,â⬠creates an extension of Kafkaââ¬â¢s life throughRead More Mental Isolation in Franz Kafkas The Metamorphosis Essay1428 Words à |à 6 Pagesin Franz Kafkas The Metamorphosis The metamorphosis very possibly was written by Kafka as an outlet for his feelings of isolation and helplessness. In it, the protagonist, Gregor Samsa, awakens one morning to find himself spontaneously transformed in his bed into a monstrous vermin. The story continues from there in a most realistic fashion: his family rejects him, and he stays cooped up in his room until he dies. Although interpretations of the story differ, my opinion is that Kafka wroteRead MoreThe Metamorphosis By Franz Kafka Essay1496 Words à |à 6 Pagesââ¬Å"The metamorphosis,â⬠is a story by Franz Kafka, published in 1915 is a story divided in three chapters: transformation, acceptance, and the death of the protagonist. There are many interpretations that can form this tale as the indifference by the society that is concerned with different individuals, and isolation pushing some cases to the solitude. Some consider The Metamorphosis as an autobiography of the author, which tries to capture the lonel iness and isolation that he felt at some pointRead MoreFranz Kafka s The Metamorphosis Of My Existence1096 Words à |à 5 PagesThe Metamorphosis of Franz Kafka A picture of my existence... would show a useless wooden stake covered in snow... stuck loosely at a slant in the ground in a ploughed field on the edge of a vast open plain on a dark winter nightâ⬠. ââ¬â Franz Kafka The Metamorphosis (Die Verwandlung 1912), Franz Kafkaââ¬â¢s best known short story, is a master work of incredible psychological, sociological and existential malaise. Although his points are simple and straightforward, this richly layered and texturedRead MoreAnalysis Of Kafka s The Metamorphosis 1166 Words à |à 5 PagesKafka is ranked among the most important writers of the twentieth century for works that express modern humanity s loss of personal and collective order. His writing describes the situations of psychological, social, political, and physical instability and confusion that defy logical explanation and which typify Kafka s conception of humanity s absurd relationship with the universe (Kafka, 2013). Although Kafka s work has elicited various critical interpretations, he himself characterized hisRead MoreAnalysis Of The Metamorphosis1501 Words à |à 7 PagesBeveridge, A. (2009). Metamorphosis by Franz Kafka. Advances in psychiatric treatment, 15(6), 459-461. This brief article is written from the psychiatric perspective, pointing out that Kafka has always been of great interest to the psychoanalytic community; this is because his writings have so skillfully depicted alienation, unresolved oedipal issues, and the schizoid personality disorder and The Metamorphosis is no exception to this rule. While this writer tends to think that psychiatrists shouldRead More The Metamorphosis Essay1716 Words à |à 7 PagesThe Metamorphosis The longer story The Metamorphosis, first published in 1971, was written by Franz Kafka. He was born in Prague in 1883 and lived until 1924, and he has written many other stories along with The Metamorphosis. The Metamorphosis appears to be a fantastic piece. After reading The Metamorphosis, I do believe that there are many similarities between magical realism and fantastic literature. Kafka showed many fantastic issues in The Metamorphosis. While reading The MetamorphosisRead MoreThe Trial And The Metamorphosis2538 Words à |à 11 Pagesand The Metamorphosis are the two foremost works Franz Kafka has ever written. By doing this, Franz makes the similarities and differences very obvious, yet each text is complex in their own way. In The Trial and The Metamorphosis, Kafka uses unique aspects to compare the characters in each novel. Each character is being forced by anonymous forces. They both go through loneliness to find the meaning behind their suffering. Each similarity and difference in The Trial and The Metamorphosis, come alongRead MoreThe Cherry Orchard By Anton Chekhov And Metamorphosis2447 Words à |à 10 Pageswas written by Anton Chekhov and Metamorphosis written by Franz Kafka. As a class we first read the plays and then explored these plays through a series of workshops and as a result this helped deepen my understanding of the plays and help develop and strengthen my acting skills. Social Cultural Historical and Political The Cherry Orchard Social: Social change is one particular theme that is mentioned throughout the play. In one workshop we looked at Ken Johnson s idea on status to deepen our understandingRead MoreAnalysis Of Franz Kafka s Life1811 Words à |à 8 Pagesphilosophy that is often analyzed through literature. Franz Kafka is a key example of the limitless nature of this theme as his many works are divisive in how they connect with existentialism. Kafka is a unique storyteller and his stories have captivated generations since their publications. His background is important in understanding his seeming detachment from his writing. Kafkaââ¬â¢s life is described by Ritchie Robertson in ââ¬Å"Biography of Franz Kafkaâ⬠as ââ¬Å"strikingly ordinaryâ⬠with the only notable commentary
Wednesday, May 6, 2020
Molecular Mechanisms, Symptoms and Treatments in Cystic Fibrosis Free Essays
string(121) " to act quickly and maybe prevent other more serious problems, related to cystic fibrosis developing later in life\[7\]\." Introduction Cystic fibrosis is a genetic disorder currently affecting over 9000 people living in the United Kingdom alone, with millions of people carrying the faulty recessive gene responsible for the disease. This essay is split into 4 distinct sections, firstly looking at the faulty gene and its effects on the organs of the body, followed by an in-depth look at the symptoms of patients suffering with cystic fibrosis, whereas the third section will look at the treatments available to sufferers. The forth section will contain potential future cures and treatments for the cystic fibrosis. We will write a custom essay sample on Molecular Mechanisms, Symptoms and Treatments in Cystic Fibrosis or any similar topic only for you Order Now Molecular Mechanisms The faulty gene that codes for cystic fibrosis affects organs such as the lungs and pancreas. This fault causes high mucosal build up in these organs. Noticeably with regards to the lungs as the high volume of mucous can cause severe breathing difficulties. The cystic fibrosis transmembrane regulator (CFTR) protein is coded for by the CFTR gene, in chromosome 7 of the human genome. CFTR is a glycoprotein made up of 1480 amino acids consisting of 5 domains. The CFTR protein is responsible for a variety of functions in the apical membranes of cells including the transport of chloride ions, regulation of the sodium ion channels and the regulation of hydrogen carbonate ion transport across the apical membrane[3]. However, it seems that the main contributing factor to cystic fibrosis is the transportation of chloride ions across the apical membrane and sodium ion regulation. Mutations in the CFTR gene can be categorized into 6 classes; depending on the effect they have on the production of the CFTR protein. The mutations are listed below in Figure 1, with the consequence of the mutation on the CFTR protein. Mutation NumberConsequence of Mutation INot synthesised IIInadequately processed IIINot regulated IVShows abnormal conductance VPartially defective production VIAccelerated degradation Figure 1 ââ¬â Table showing the Mutation Number and the Consequence of the mutation on the CFTR protein The mutations stated in figure 1, either cause the CFTR protein to become ineffective or prevents synthesis altogether. Classes I and III prevent synthesis of the CFTR protein, whereas other mutations cause problems in the production of the protein. Class II mutations effects can vary from the CFTR protein being completely dysfunctional to significantly reduced function depending on the patient. Class IV and Class V mutations do not cause the CFTR protein to cease working, but do have a derogatory effect on their function. Class VI mutations cause before-time degradation of the protein meaning reduced function. One of the consequences of the CFTR protein not functioning in cystic fibrosis patients is a high concentration of chloride ions developing in the intracellular space, as well as little regulation of sodium ions entering the cell. Under normal circumstances water would diffuse out the cell and contribute to the airway surface liquid as the concentrations of chloride and sodium ions would be higher in the extracellular space. However with a defective CFTR gene the osmotic gradient is reversed. Thus leading to a high ion concentration within the cell and depletion in the airway surface liquid. Cilia are small hair like projections in the respiratory tract which are responsible for wafting the mucous up the respiratory tract so it can be swallowed and infection averted. Mucous is one of the bodyââ¬â¢s primary physical defences against bacterial infection. Pathogens capable of causing respiratory disease are caught on the mucous in the respiratory tract and eventually swallowed with the aid of cilia thus avoiding the entry of pathogens into the lungs and causing bacterial infection. Airway surface liquid also prevents infection by facilitating the movement of mucous up the respiratory tract. However when there is depletion in airway surface liquid, the cilia are also affected. The mucous therefore needs to be of low viscosity so it can be easily moved up the respiratory tract. However, due to the lack of airway surface liquid in a patient with cystic fibrosis the mucous becomes static and more viscous leading to bacterial infections in the lungs. Cystic Fibrosis does not just affect the lungs in some cases. Occasionally, the pancreas and in the case of men, reproductive organs can be affected. This all depends on which class of mutation of the CFTR gene the patient has as patients with Class I, II and III are prone to pancreatic insufficiency3. In normal pancreatic exocrine secretion, the digestive enzymes secreted from pancreatic gland cells, are mixed with a bicarbonate-rich fluid, secreted from duct cells and released into the small intestine to aid in the digestion of food. The function of the pancreatic gland cells remains fairly constant, but there is a noticeable difference in secretion of the bicarbonate-rich fluid from the duct cells. Thickening secretions causes the duct releasing fluids into the small intestine becomes blocked by enzymes precipitating as well as mucosal build up. With the ducts becoming more blocked, the pressure inside the pancreas increases and as the pancreas lacks structures aiding in support i s therefore very prone to damage. Symptoms Cystic fibrosis effects different organs around the body and therefore gives rise to a vast range of symptoms. The organs most heavily affected by cystic fibrosis are the lungs and the pancreas, and in males, the reproductive organs are affected. The most obvious indication that a patient may have cystic fibrosis would be a family history of the disease. As cystic fibrosis is a genetic disorder, the faulty recessive gene can be passed to children. Due to the gene being recessive, it is possible for parents to be a carrier for cystic fibrosis but not express any symptoms themselves. Therefore if both parents are carriers of the gene, then there is a 25% chance of the offspring having cystic fibrosis. From 2009 onwards it is required for new-born babies in the USA to be screened for genetic disorders like cystic fibrosis. If positive, it gives doctors an opportunity to act quickly and maybe prevent other more serious problems, related to cystic fibrosis developing later in life[7]. You read "Molecular Mechanisms, Symptoms and Treatments in Cystic Fibrosis" in category "Essay examples" Other common symptoms that are shown by most ages are salty tasty skin, clubbing of the fingers and toes, coughing with sputum production, mucoi d Pseudomonas aeruginosa isolated from airway secretions and hypochloraemic metabolic alkalosis[8]. The symptoms shown by the patient are also different depending on their age. Figure 2 shows a table listing the symptoms by age they become prevalent. NeonatalInfancyChildhoodAdolescence and Adulthood Meconium ileusPersistent infiltrates on chest radiographs Chronic pansinusitis or nasal polyposisAllergic bronchopulmonary aspergillosis Protracted jaundiceFailure to thriveSteatorrhoea Chronic pansinusitis or nasal polyposis Abdominal or scrotal calcificationsAnasarca or hypoproteinaemiaRectal prolapseBronchiectasis Intestinal atresiaChronic diarrhoeaDistal intestinal obstruction syndrome or intussusceptionHaemoptysis Abdominal distentionIdiopathic recurrent or chronic pancreatitisIdiopathic recurrent pancreatitis CholestasisLiver diseasePortal hypertension Staphylococcus aureus pneumoniaDelayed puberty Idiopathic intracranial hypertension (vitamin A deficiency)Azoospermia secondary to congenital bilateral absence of the vas deferens Haemolytic anaemia Figure 2 ââ¬â Depending on the age of the patient, different symptoms for Cystic Fibrosis will be apparent shown in the table above8 As shown in Figure 2, cystic fibrosis has a big effect on many parts of the body. However, the main problem for a patient with cystic fibrosis remains pulmonary disease and the effect of the gastrointestinal problems which arise. Innate defence mechanisms like the physical barrier provided by the mucous, lining the respiratory tract, is inefficient at its function in a patient with cystic fibrosis. This therefore leads high levels of bacterial infection and inflammation. The bacterial infections begin soon after birth with Staphylococcus aureus and Haemophilus in?uenzae usually being the pioneer bacteria causing primary infection in the lungs of a patient. It has been suggested that these bacteria are responsible for damaging the epithelial surface cells and therefore aiding other bacteria bind to the surface, however this is still under debate by scientists. However, Pseudomonas aeruginosa is the organism responsible for the later, fatal infections that cause the highest mortality rate in patients with cystic fibrosis. The CFTR protein not only has functions transporting ions, but it is also thought to have a role in binding molecules of Pseudomonas aeruginosa. In a normal individual, Pseudomonas aeruginosa binds to the CFTR protein, and a rapid and self-limiting in?ammatory response9 occurs removing the infection from the respiratory tract. This explains why Pseudomonas aeruginosa is the main causative agent of pulmonary disease in cystic fibrosis sufferers. Symptoms of cystic fibrosis caused by gastrointestinal problems are mainly caused by the inability to digest food. As mentioned above the ducts leading to the small intestine, which would carry a liquid, containing digestive enzymes is blocked. This causes the pancreas to come pressure and gets damaged. The symptoms caused by this inability to digest food are greasy stools, flatulence, abdominal bloating, and poor weight gain8. At the time of its discovery, malnutrition was the main cause of death due to the inability to produce the enzymes in the pancreas to digest food. Malnutrition can now be treated using pancreatic enzyme replacement therapy8, however other factors like the poor adsorption of fat soluble vitamins can lead to acrodermatitis, anaemia, night blindess, neuropathy, osteoporosis and bleeding disorders8. A high percentage of Cystic fibrosis patients can develop Cystic Fibrosis related Diabetes Mellitus (CFRD) due to the pancreatic damage that is done by the blocking of the ducts within in the pancreas. The Islet of Langerhans produces insulin and glucagon to regulate blood glucose concentrations. Insulin stimulates the formation of glycogen, removing glucose from the blood stream whereas glucagon stimulates the breakdown of glycogen. With the pancreas undergoing autolysis, it is inevitable that these cells will become damaged and unable to produce a sufficient amount of insulin. However, CFRD is different to diabetes mellitus I and II. The specific symptoms affected by cystic fibrosis are glucose metabolism, acute and chronic infection, glucagon deficiency, liver dysfunction, decreased intestinal transit time, and increased work of breathing8. Cystic fibrosis also affects male reproduction. In the male reproduction organs, the vas deferens is responsible for the transfer of sperm from the epididymis in anticipation of ejaculation8. Male patients with cystic fibrosis lack this muscular tube and therefore there is no sperm in their ejaculate. Women however are fertile, but careful control of nutritional intake must be taken to ensure the full term of pregnancy and subsequent birth can be achieved. I can be possible for parents to pass the gene for cystic fibrosis onto their children. As a man expressing the disease being infertile the recessive gene must come from a carrier of cystic fibrosis but not expressing any symptoms. If the female sufferers from cystic fibrosis then there is a 50% chance that the child will also have the disease. However if the female is also a carrier of the recessive gene then there is a 25% chance that the child will have cystic fibrosis. Current Treatments As it stands at the moment, cystic fibrosis cannot be cured. Cystic fibrosis is a genetic disease, and therefore there is an error in the DNA of cells of an individual apart from their gametes. This means that the only available option to sufferers is to find drugs to treat the various symptoms. However in recent years there have been successful attempts to find drugs to resolve the original defects. Patients with cystic fibrosis often suffer from severe pulmonary infections, as they are less efficient at swallowing mucous containing pathogens. The airway surface liquid and cilia, as discussed above are responsible for the movement of mucous up the respiratory tract in a normal individual. Cystic fibrosis sufferers lack the required volume of airway surface liquid. One such treatment, looking to solve the problem caused by the faulty gene is hypertonic saline. Hypertonic saline is the current drug used to bring about an increase in the volume of airway surface liquid in the lungs of the patients. It has been shown by researchers that in vitro, hypertonic saline is effective with rehydrating and providing more airway surface liquid8. If from an early age there is aid with mucosal clearance from the respiratory tract, it would reduce the chances of the patient developing severe bacterial infections from pathogens such as pseudomonas aeruginosa. Antibiotics are also important to control pulmonary bacterial infections that occur from poor mucosal clearance. Macrolide antibiotics are cheap antibiotics used to treat cystic fibrosis sufferers. They work by inhibiting the bacteria protein biosynthesis; however the precise mechanism they use is currently not fully understood. Macrolides have a dual function in the cystic fibrosis treatment. They affect cytokine production of many cell types and are therefore effective as anti-inflammatory agents8. One study showed that taking azithromycin three times a week reduced the virulence factor production, decreased biofilm production, bactericidal effects on pseudomonas aeruginosa growing in stationary phase8. Patients with gastrointestinal symptoms brought about by cystic fibrosis require other forms of treatment, as they unable to produce enough enzymes to digest their food. Enzymes are usually secreted from the pancreas into the small intestine, allowing the individual to digest their food. However a patient with pancreatic insufficiency is unable to secrete the enzymes into the small intestine due to the intrapancreatic ducts being blocked. This needs to be treated as patients are at risk of severe malnutrition if food cannot be fully digested. Pancreatic Enzyme Replacement Theory (PERT) is used to treat this problem. The enzymes used in PERT are taken with every meal to aid in the absorption of food in the small intestine. This does not solve the underlying problem caused by cystic fibrosis, and can only treat the symptoms. This is because the enzymes do not last for a great deal of time in the body; the reason why enzymes must be taken with every meal. Chest physiotherapy can aid in the treatment of a sufferer as it can help in mucosal clearance from the pulmonary tract[11]. Some methods focus on the way the patient breathes which include active cycle of breathing techniques, and autogenic drainage11. However some techniques focus on actual mucosal clearance like positive expiratory pressure (PEP) oscillating positive expiratory pressure11. The final and most severe treatment used to use the chronic pulmonary disease is lung transplantation. This procedure comes with high risk with only 50% children surviving 5 years after the transplant and 50% of adults surviving 6 years after the transplant8. Future Treatments As of yet there is no cure for cystic fibrosis, however there are promising new drugs on the horizon which could one day all but cure the genetic disease. A drug that is combatting the ââ¬Å"basic defectâ⬠of cystic fibrosis is VX-770 made by Vertex pharmaceuticals. This drug is currently undergoing trials in the United States of America and is showing promise for improving lung function in those affected by cystic fibrosis. The drug itself targets the chlorine channels in the apical membrane, opening them to allow chlorine to leave the epithelial cells. Results from the recent Phase 3 clinical trials showed that there was a 10% increase in lung function in people aged 12 and above, and a 12.5% increase in lung function for those from ages 6 to 11. The drug also decreased the concentration of chlorine in sweat and allowed the patients taking the drug to gain on average 7 pounds12. Pancreatic insufficiency usually makes it hard for the cystic fibrosis patient to gain weight, meaning the drug has an effect on gastrointestinal symptoms as well as respiratory symptoms. The idea of gene therapy is a concept that has been around for a while. The Cystic fibrosis gene therapy consortium was set up in 2001 to focus on developing new ways to combat cystic fibrosis and the symptoms. In February 2009, the consortium made a step closer to find a ââ¬Å"gene therapy cureâ⬠for cystic fibrosis. They managed to insert successfully, a working CFTR gene into a viral vector, which was then transported into the lungs of a cystic fibrosis patient. Whereas the idea itself is good, there are some drawbacks. The viral vector itself comes under attack from the immune system as well as viral vectors being poor at inserting DNA into epithelial cells8. Therefore the The Cystic fibrosis gene therapy consortium has been looking at using lipid vectors currently with little success. They have reported that currently gene expression in the cells that do take up the gene is currently temporary and they are looking into methods to provide sustained gene expression in the ep ithelial cells. Not all mutations cause the CFTR protein not to be synthesised. Some mutations cause the CFTR protein to be marked for degradation as the chaperones, aiding with folding the protein, do not dissociate from the protein8. There have been tests in labs using chemicals such as phenylbutyrate8, however any further developments in this field of research. Conclusion It is remarkable how such a small difference in the DNA of an individual can have so much effect on the patientsââ¬â¢ health. However the future looks bright for those patients suffering with cystic fibrosis. There is a huge amount of research taking place in order to find new treatments and potential cures for the disease. Recently, research has shifted from looking for ways to treat the symptoms, to methods of treating the underlying problems behind the disease. For example a drug called VX-770 made by Vertex Pharmaceuticals, focuses on the inefficient chlorine channels in the epithelial cells. If cystic fibrosis remains a continually financially backed area of research, there is no reason why significant progress cannot be made sooner rather than later. How to cite Molecular Mechanisms, Symptoms and Treatments in Cystic Fibrosis, Essay examples
Friday, May 1, 2020
The Food Safety Measures in Australia â⬠MyAssignmenthelp.com
Question: Discuss about the Food Safety Measures in Australia. Answer: The main cause of food contamination in Australia is the microbial contamination. The microbes can grow and multiply in different foods that they consume. The increased compliance of microbial contamination will bring in the most leading microbe the Salmonella. The causes and effects of the different microbes Salmonella This particular microbe is mainly associated with the livestock and the chicken food, poultry. The food poisoning is associated with the not well cooked food or not adequately cooked eggs, unpasteurized diary and raw milk and cheeses. The effect of Salmonella infection is that it will lead to gastro flu like disease. The disease is called the Salmonellosis. Prevention will include the exclusion of the people bearing the Salmonella infection. The food should be well cooked. There should be strict measures in handling the food (Zwietering et al, 2016). Campylobacter This bacteria cause food poisoning called the campylobacteriosis. They are also the common cause of diarrhea in Australia. They are often found to be poisoning the food that is undercooked. The supermarket chickens are mainly contaminated with this type of bacteria. People should be extra care while handling the cooking stuffs. The hands should be well cleaned and sanitized while chopping or using the utensils. Listeria Listeria monocytogenes comes from the cooking place. The pregnant women and the children who have less immune system gets more chance to be affected by the disease. They mainly contaminate the seafood, precooked deli meats, premixed raw vegetables. To promote safety from this microbe one should see to the maintenance of the workplace with hygiene maintence and. The raw materials that is to be well washed (Luning et al, 2015) Golden staph They infect the persons through the cut in the skins and the symptoms of the disease may cause sore throat and swelling, blisters and impetigo. The poultry, eggs and diary are mainly contaminated with this microbe. The people who are touching food must continuously wash their hands and also use sterile disposable gloves. Clostridium perfringens Not appropriate cooked food and refrigerated food are the main source of C. perfringes cells that cause food poisoning. They cause Diaarhea and abdominal disorders. The older people and infants are highly susceptible to this. The preventive measures will include well cooked food. There should be use of the food thermometer. The food should be kept hot after cooking and then should be consumed. Bacillus cereus It causes abdominal disorders. These bacteria produce toxins that lead to the food poisioning. The main safety measure that can be taken is that if the food is stored for longer than 2 hours or if the food is cold about 400F they should be well heated before consuming (Keuckelaere et al, 2015) Case studies Risk Reason of risk prevention The casual staff in the hotel had cut in the hand The food left for hours The food left in the refrigerator The staff if infected with any microbes than the other persons consuming it will be affected. This could be another reason for food poisoning due to microbes as the long hour time is enough for the microbe to grow The cold condition is favorable for the microbes to grow. These will include proper handling of the food and the food should be heated before it is consumed (Mcauley et al, 2014). References Keuckelaere, A., Jacxsens, L., Amoah, P., Medema, G., McClure, P., Jaykus, L. A., Uyttendaele, M. (2015). Zero risk does not exist: lessons learned from microbial risk assessment related to use of water and safety of fresh produce.Comprehensive Reviews in Food Science and Food Safety,14(4), 387-410. Luning, P. A., Kirezieva, K., Hagelaar, G., Rovira, J., Uyttendaele, M., Jacxsens, L. (2015). Performance assessment of food safety management systems in animal-based food companies in view of their context characteristics: a European study.Food Control,49, 11-22. Mcauley, C. M., McMillan, K., Moore, S. C., Fegan, N., Fox, E. M. (2014).Prevalence and characterization of foodborne pathogens from Australian dairy farm environments.Journal of dairy science,97(12), 7402-7412. Zwietering, M. H., Jacxsens, L., Membr, J. M., Nauta, M., Peterz, M. (2016). Relevance of microbial finished product testing in food safety management.Food Control,60, 31-43.
Saturday, March 21, 2020
English Literature Coursework
English Literature Coursework English Literature Coursework English literature is full of wonders and interesting facts. If you choose to work on this topic, you will have to work hard, but it will not leave you indifferent. The fact that it is an important step is based on the figures - English literature coursework makes 30% of the grade which a student receives for the course on English literature. Writing English literature coursework means to work hard on the class assignments, certain materials, topics, describing the main genres, styles and other aspects. To write an excellent English literature coursework you should: think critically to provide a good analysis; make a composition logical and in accordance to format requirements; find such an approach to the study which requires critical thinking skills. You may use following tips for English literature coursework: You will work on the paper faster and more efficiently if you choose a topic which is interesting for you. When you must find information for your English literature coursework, it means I will do it tomorrow and Why do I have a low grade?. But when you want to find more facts and information, it is only Yes, I have done it!. Next point which you will never forget is deadline. You must write and hand in your English literature coursework by the specified time, otherwise, your grade will be shared on as many pieces as many faults you have done during writing. Your schedule of writing on the paper should be based on your own preferences and energy. To do everything to write a coursework does not mean to do anything 3 months and then to write a whole paper overnight. No, you can work at night or in the morning, you can write in the bus or in the caf, you can ask for an advice from a passerby or think out a special offer do everything that makes sense and you will do a step on the right way. Do not ignore your class notes; maybe the instructor has given certain rules or hints which will be useful for you in the process of writing. And be attentive while editing it is also an important stage in the writing process, for a student does not give attention to the parts he or she counts perfect. Do not overestimate yourself. Do not be afraid of speaking with your advisor it can be a good choice, especially if you do not know how to start your work or choose the topic. Advantages and disadvantages of the writing English literature coursework can be thought out by you, but you can make your paper excellent. Do it! If you cannot trust yourself in dealing with time, literature material or original thought, you can always ask us for professional help with English coursework writing: Relatedposts: Sample Papers Report Writing Help Process Analysis Case Study Merchant of Venice Critical Essay Little Prince Reaction Paper
Thursday, March 5, 2020
The Difference Between Control Group and Experimental Group
The Difference Between Control Group and Experimental Group In an experiment, data from an experimental group is compared with data from a control group. These two groups should be identical in every respect except one: The difference between a control group and an experimental group is that the independent variable is changed for the experimental group, but is held constant in the control group. Key Takeaways: Control vs. Experimental Group The control group and experimental group are compared against each other in an experiment. The only difference between the two groups is that the independent variable is changed in the experimental group. The independent variable is controlled or held constant in the control group.A single experiment may include multiple experimental groups, which may all be compared against the control group.The purpose of having a control is to rule out other factors which may influence the results of an experiment. Not all experiments include a control group, but those that do are called controlled experiments.A placebo may also be used in an experiment. A placebo isnt a substitute for a control group because subjects exposed to a placebo may experience effects from the belief they are being tested. What Are Groups in Experiment Design? An experimental group is the group that receives an experimental procedure or a test sample. This group is exposed to changes in the independent variable being tested. The values of the independent variable and the result on the dependent variable are recorded. An experiment may include multiple experimental groups at one time. A control group is a group separated from the rest of the experiment such that the independent variable being tested cannot influence the results. This isolates the independent variables effects on the experiment and can help rule out alternative explanations of the experimental results. While all experiments have an experimental group, not all experiments require a control group. Controls are extremely useful where the experimental conditions are complex and difficult to isolate. Experiments that use control groups are called controlled experiments. A Simple Example of a Controlled Experiment A simple example of a controlled experiment may be used to determine whether or not plants need to be watered to live. The control group would be plants that are not watered. The experimental group would consist of plants that receive water. A clever scientist would wonder whether too much watering might kill the plants and would set up several experimental groups, each receiving a different amount of water. Sometimes setting up a controlled experiment can be confusing. For example, a scientist may wonder whether or not a species of bacteria needs oxygen in order to live. To test this, cultures of bacteria may be left in the air, while other cultures are placed in a sealed container of nitrogen (the most common component of air) or deoxygenated air (which likely contained extra carbon dioxide). Which container is the control? Which is the experimental group? Control Groups and Placebos The most common type of control group is one held at ordinary conditions so it doesnt experience a changing variable. For example, If you want to explore the effect of salt on plant growth, the control group would be a set of plants not exposed to salt, while the experimental group would receive the salt treatment. If you want to test whether the duration of light exposure affects fish reproduction, the control group would be exposed to a normal number of hours of light, while the duration would change for the experimental group. Experiments involving human subjects can be much more complex. If youre testing whether a drug is effective or not, for example, members of a control group may expect they will not unaffected. To prevent skewing the results, a placebo may be used. A placebo is a substance that doesnt contain an active therapeutic agent. If a control group takes a placebo, participants dont know whether they are being treated or not, so they have the same expectations as members of the experimental group. However, there is also the placebo effect to consider. Here, the recipient of the placebo experiences an effect or improvement because she believes there should be an effect. Another concern with a placebo is that its not always easy to formulate one that truly free of active ingredients. For example, if a sugar pill is given as a placebo, theres a chance the sugar will affect the outcome of the experiment. Positive and Negative Controls Positive and negative controls are two other types of control groups: Positive control groups are control groups in which the conditions guarantee a positive result. Positive control groups are effective to show the experiment is functioning as planned.Negative control groups are control groups in which conditions produce a negative outcome. Negative control groups help identify outside influences which may be present that were not unaccounted for, such as contaminants. Sources Bailey, R. A. (2008). Design of Comparative Experiments. Cambridge University Press. ISBN 978-0-521-68357-9.Chaplin, S. (2006). The placebo response: an important part of treatment. Prescriber: 16ââ¬â22. doi:10.1002/psb.344Hinkelmann, Klaus; Kempthorne, Oscar (2008). Design and Analysis of Experiments, Volume I: Introduction to Experimental Design (2nd ed.). Wiley. ISBN 978-0-471-72756-9.
Monday, February 17, 2020
The Reality of Work Cultures in the Modern Economy Essay
The Reality of Work Cultures in the Modern Economy - Essay Example Work culture plays a significant part in bringing the best out of workers and enabling them stay in the work place for a prolonged period. Work culture is significant as it leads to contented workers and enhanced productivity. Richard Sennett asserts that individualsââ¬â¢ work culture will be defined by the novel ideas of flexibility, decentralization and control, flextime, work ethics and teamwork, and change. Moreover, the stated concepts have an impact on character as articulated by commitment and loyalty and eventually lead to the lessening of personal traits and values that are attractive in society (Sennett 1999, p. 9). The modern way of working makes it extremely demanding to get a life as asserted by Sennett. He claims that the personal effects of work in the New Economy have made the individual to be disoriented due to notions such as flexibility, decentralization and control, flextime, work ethics and teamwork, and change. In the contemporary way of life, there has been a spatial modification of work activities on a universal degree, as space and geography have become significantly essential components of work, labour relations, and labour markets (Sennett 1999, p. 9). This means that workers will use most of their time trying to engage in activities that will help them adapt to new working requirements, therefore, it will be difficult for them to get a life. Nonetheless, modern way of working has enhanced connections between individuals, nations, and organizations. This has been made possible by developments in technology and has made it extremely simple to transport people, capital, and commod ities in and across regions as a rapid speed. This has also made employers, customers, and employees focus solely on work activities, and losing their individual existence, hence not getting a life. In addition, the modern way of working has liberated employers from standard spatial and temporal restrictions and facilitated them to position their work activities finely and to gain inexpensive sources of labour. Therefore, workers who provide their labour in exchange for low wages cannot have a life simply because their income cannot match their needs (Golden 2001, p. 240). Moreover, the modern way of working entails developments in communication and information technologies. These advances permit capitalists to impose restraint over spatially and decentralized distributed labour processes. Also, in the contemporary way of working, an individual has to engage in activities that will maintain and enhance their job skills. This will help them to keep up with shifting job needs. Numerou s people find it demanding to find ways of staying employable in a rapid-changing working environment in which talents become quickly out of date. Unlike employees of the early periods, modern day workers are most probable to go back to school or engage in activities that will enhance their talents as they change careers. This will make it difficult to get a life as argued by Sennett. Sennett highlights flexibility, decentralization and control, flextime, work ethics and teamwork, and change as the issues which lead to the corrosion of character. For Charles Stuart Mill flexibility signified the source of individual freedom and which continues to have an impact on our comprehension of the flexibility notion. Sennett asserts that search for flexibility has lead to the development of new structures of control
Monday, February 3, 2020
Economics Term paper Example | Topics and Well Written Essays - 1500 words
Economics - Term Paper Example In various means, advertising and customer researchers continuously encounter the test of making images that depict respondents to marketing-related stimuli, this represents as a data for purposes of analysis. This data will incarcerate the fundamental nature of significant utilization practices; that will be communicated to research findings for interested audiences; or play a role in executing the pictorial components of marketing stratagem (Morris, 1997). Generic advertising was the common methodology used in enticing consumers to purchase a product or avail a certain service. This method captures the public attention in an instant, but this will not sustain if the advertisement is boring and dry. The generic approach is very important in preparing advertising messages that concentrates on the customer benefits that apply to all brands in a product category, as opposed to benefits that are unique to specific brands. Rather than being generic, companies and advertising agencies are finding effective means and faster communication of messages to the direct consumers. In the new millennium, the internet-based technology has played a key role in expanding a wide array of consumers in a small span of time worldwide. The potential of the World Wide Web on the Internet as a commercial medium and market has been widely documented in a variety of media. However, a critical examination of its commercial development has received little attention (Ricciuti, 1995). In this fast-paced environment, technology was always an important tool in spreading the good news and to easily communicate with direct customers. The development of internet-based technologies opened endless possibilities for Marketers. Marketing research can be carried out subtly by actively archiving the procedures that each individual undertakes on the Web, through Web tracking software (Culnan, 1999). When we make a whole new set of variables available to the marketer, the
Sunday, January 26, 2020
Impact of Uber on UK Mini Cabs
Impact of Uber on UK Mini Cabs Introduction The intense rivalry among competitors in the market is a critical driving force for each organisation. A healthy competition among competitors builds fuel for organisation long run, and while seeking progress firm practices influences other companies in the industry. The present research enables the researcher to find out such influences produced by Uber through their innovative practices. The research attempt shed lights on Uber Cab Company performance and the impact made by the organisation on other minicabs in the UK taxi industry. The researcher looks to utilise the journals of Wallsten (2015) and Edward, George and Sarkar (2010) for perceiving current issues efficiently. The investigation tries to perceive strategies and practices executed by Uber to advance in the UK taxi industry along with identifying the influence made on minicabs performance. Literature review The rise of Uber and the subsequent disruption in taxi industry has been a key research issue in recent years. For example, the study of Sundararajan (2014) revealed that the success of Uber was mainly due to the convenience offered by the service compared to existing cab services. This view has been upheld by other researchers such as Malhotra and Van Alstyne (2014) and Isaac (2014). All these studies point to the fact that Uber offer higher value to taxi customers in terms of lower charge, higher convenience and better safety offered by Uber. The theory of quality-value-loyalty chain was used by Wallsten (2015) to evaluate the success of Uber in Taxi industry. Figure 1.1: Quality-value-loyalty chain Source: Wallsten (2015) As per Quality-value-loyalty chain, price, product quality and service quality develop the perceived value of a product or service which in turn contributes to customer loyalty towards the product or service. Among these elements, competitors are easily able to imitate product quality and price. But it is very difficult to imitate service quality (Edward, George and Sarkar, 2010). Due to this, service quality has an enhanced role in creating value and loyalty for the product or service. Wallsten (2015) notes that the superior service quality of Uber has helped the company in creating value for customers and in developing loyal customer base in taxi industry. From the review of existing literature available on Ubers success in taxi industry, it can be understood that the ability of the company to offer better value, service quality and convenience was the main reasons for its success. Research purpose The study intends to identify the impacts that created by Uber Cab Company in the UK taxi industry and analyse influence that the company made on minicabs in the country. à à The research objectives of the current research are: To evaluate the factors affecting satisfaction of cab customers To assess the factors contributing to the competitive advantage of Uber in UK Taxi industry To analyse the impact of Ubers growth on mini cabs of UK To provide suggestions to mini cabs of UK to remain competitive in UK Taxi industry Rationale Despite being a start-up in the UK taxi industry, Uber cab services had provided growth to the traditional taxi service in the country. The process made the countrys private taxi firm to stand tall where other numerous taxi companies had failed. According to Megaw (2016), 97% of the organisation that tried fit their name in the industry had fallen within the first four months where Uber showed resilience in making an impact which flew beyond the capital. The company had expanded beyond borders leaving a note on taxi industry to look for an urgent lift in which the mini cabs have experienced most of the damage. Uber was able to advance in each market that they have entered which led to protests and strikes in the UK. Uber Cab company flexibility had attracted few drivers who worked in mini cabs in London to join in the company. The low pricing strategy that the company presented has made controversies as competitors had alleged the practice unhealthy and artificial. Uber started its o peration in the UK with four locations and increased the size to eighteen with 30,000 drivers in London (Torrance, 2016). Data analysis interprets that since Uber started its operation, the private hire operations in London has attained a decline of 11% assuming minimum ten private taxi business close in every month. The research seeks to identify major reasons for the customer to choose Uber cab over minicabs by comparing their service using service quality framework and looks to interpret recommendation for minicabs in order to survive the situation. Scope and limitation of research The Uber Cab Company intervention to the UK taxi industry has been questioned severely by the minicab operators as their low payment system and other operations has affected minicabs and provoked few operators to end their operations in London area. The investigation gathers ample evidence for interpreting the features that attracted customers to Uber service so that certain recommendations could be drawn to the minicab operators in the UK for improving their business in the location. Research methodology For constituting the study, the researcher has to acquire efficient information on operations of both Uber Cab and minicab services. For carrying out the research both primary and secondary data collection method is used by the researcher. The literature and journals on the topic are utilised to attain secondary data, and the primary information is collected through executing a survey on taxi customers. The survey is conducted on 55 customers who use taxi services in London in which 30 female and 25 male customers are targeted. The survey method enables researcher to understand consumer perspectives on services provided by Uber Cab and minicab companies improving study strength. The data achieved from books, journals, articles and websites belong to the secondary resources which are used by the researcher to analyse the issue further. The adequate information attained from these practices is used to provide significant interpretations for present research problems from which efficien t recommendations are drawn for the minicab operators. Action plan à à à Research objective By when Resources to be used (2.1) when do you know this objective is achieved which is after the by when to ensure that you have actually achieve the objective How will you monitor this objective is being achieved? method of monitoring Topic selection 17th December to 22nd December 2017 Books, articles and online journals for study topic selection 21st December 2017 22nd December 2017 Reporting Regularly to supervisor Aim and objective preparation 23rd to 24th December 2017 Adequate journals and books 23rd December 2017 24th December 2017 Reporting Regularly to supervisor Literature review 25th December to 10th January 2017 Secondary resources like books and publications both online and offline for literature review preparation 8th January 2017 10th January 2017 Timely informing supervisor work status updates Research methods 12th January to 16th April 2017 Journals and books for perceiving research methods 13th January 2017 15th April 2017 Updating report status to supervisor Data collection 17th January to 16th February 2017 Survey on customers as primary resource and data from books, journals and company reports as secondary resource 15th February 2017 16th February 2017 Communicating status to supervisor Interpretation of data 17th February 1st March 2017 Comparison of primary and secondary information and analysis descriptive methods 25th February 2017 1st March 2017 Updating work status to supervisor Conclusion and recommendation March 2nd 14th March 2017 On the basis of interpreted data and analysis 13th March 2017 14th March 2017 Timely report to supervisor Final submission 15th March 2017 2.2 Undertake the proposed research investigation in accordance with the agreed specification and procedures. Questionnaire design This research was deliberated to mainly evaluate the effect of UBER Cab Company on mini cabs in the UK. For conducting the study, the research has opted UBER Cab Company to carry out the study. The research has mainly opted questionnaire method so as to gather data and information from the customers of UBER Cab Company to know more about taxi and the scope of them. For developing and evolving the questionnaire, the research has adopted Likert scale method, and to the customers of UBER Cab Company, the questionnaire was distributed with the aid of survey method. By opting the customers of UBER Cab Company for conducting the survey, the data gathered by the researcher was accurate and appropriate to the question of the research. Data collection method For the study, the research decided to opt primary data collection using survey method. The research was done with the aid of survey that was carried out on the customers of a minicab in London. The researcher decided to opt about 55 as the sample size for the study where 30 were women, and 25 were men. With the aid of survey method, the researcher could gain more knowledge and understanding about the company and the taxi services. All the research questions were related to the study and the questions prepared was simple and very easy to understand. This helped the researcher to get the opinions of customers. Advantages of survey method: With the aid of primary research, the research could gain relevant, apt and specific answers when compared to any other research methods. With the aid of Likert scales, the researcher could understand more about the topic and do not spend more time on the data collection. Survey method is cost effective and time-consuming. Disadvantages of survey method: The survey that is closed and structured might have less validity and reliability than other methods. There can be favourable answers been marked by the researcher so as to support the subject. The respondents will not be able to give their maximum as they will not be aware of the reason behind the survey. Advantages and disadvantages of ANOVA method The survey method was analysed with the aid of ANOVA method through which qualitative data collection was collected. Over more than two groups the data are examined and reviewed constancy for gaining the result in the case ANOVA method. The t-test is mainly compared to ANOVA methods as instead for ANOVA method t-test is used for the similar use. The advantages of ANOVA are: ANOVA method is mainly opted to relate groups of various samples sizes when compared to the t-test. Without cumulating the probabilities of Type, I error, with the aid of ANOVA more than two grouped can be evaluated. The disadvantages of ANOVA are: Incorrect results can be gained from ANOVA if the samples are gathered from the average population. ANOVA helps to makes sure if the samples are different from each other and also indicates the samples that are different from the similar ones. D3: Justify the choice of data collection methods To get accurate and reliable data and information the researcher adopted primary research for this study conducted on UBER Cab Company. The research has adopted survey method as the research strategy to gather data from the customers of UBER Cab Company London. The responses gathered from different customers were different and had different opinion and suggestions. The questions were closed and structured through Likert scales. Likert scales also aided the researcher in understanding the questionnaire. It was comparatively easy for the researcher to gather quantitative data with the help of survey methodology that made the research to be analysed easily with the aid of ANOVA method. 2.3 Record and collate relevant data where appropriate The researcher has used ANOVA analysis for testing the data collected from taxi customers of London. The researcher collected data from 55 taxi customers (30 female and 25 male customers). The working hypothesis adopted by the researcher is that there is clear difference in taxi service preferences of male and female taxi customers of London. This working hypothesis is tested with the help of ANOVA analysis. SS df MS F P Price 388.9286 1 388.9286 9.24 0.028759 Accessibility 388.9286 1 388.9286 5.08 0.073916 Convenience 388.9286 1 388.9286 3.56 0.117844 Driver behaviour 388.9286 1 388.9286 6.69 0.049044 Quality of car 388.9286 1 388.9286 10.89 0.021476 Safety 388.9286 1 388.9286 14.9 0.011879 2.1 ANOVA analysis of customer needs from taxi service From the above ANOVA analysis it can be understood that the opinions of male and female taxi customers significantly diverge in terms of their needs and expectations from taxi services available in UK. The analysis shows that female customers gave greater importance of safety, quality of car and driver behaviour when compared to male customers. On the other hand, male customers gave higher importance to convenience aspect while choosing taxi services. SS Df MS F P Reliability 388.9286 1 388.9286 6.65 0.049507 Assurance 388.9286 1 388.9286 14.25 0.012957 Tangibility 388.9286 1 388.9286 4.12 0.098139 Empathy 388.9286 1 388.9286 11.68 0.018887 Responsiveness 388.9286 1 388.9286 2.83 0.153344 2.2 ANOVA analysis of customer rating of service quality of Uber From the ANOVA analysis of the customer rating of service quality of Uber it is clear that both male and female customers have diverging opinions regarding the different dimensions of service quality of Uber. For example, it is evident that reliability, empathy and assurance elements of service quality of were given higher rating by female customers while male customers gave higher importance to responsiveness of the service of Uber. SS df MS F P Reliability 388.9286 1 388.9286 8.36 0.034132 Assurance 388.9286 1 388.9286 5.71 0.062422 Tangibility 388.9286 1 388.9286 21.02 0.005922 Empathy 388.9286 1 388.9286 3.28 0.129892 Responsiveness 388.9286 1 388.9286 11.02 0.021017 Methodology I used simple random sample because it is the simplest way to select participants from a population. According to Saunders, et al., using these methods means that each individual in the population has the same chance of being selected for the sample (2012) The survey questionnaire was developed on free online source distributed to employees via email, and social media messaging. Printed sheets of questionnaire were also provided for data collection. The expected sample size is set to 100 participants from the target population and the sampling is undertaken based on simple random sampling method. 2.3 ANOVA analysis of customer rating of service quality of UK minicab The above analysis of customer rating of service quality of UK minicabs reveal that female customers hold very different view regarding the service of minicabs when compared to female customers. It is evident from the analysis that female customers opinion regarding the reliability, assurance, tangibility and responsiveness of minicabs diverge from that of their male counterparts. SS Df MS F P Uber 388.9286 1 388.9286 2.43 0.179774 Minicab 388.9286 1 388.9286 14.25 0.012957 2.4 ANOVA analysis of customer likelihood of using of Uber and Minicab The above ANOVA analysis shows that female customers are much more likely to not use minicabs than male customers. On the other both male and female customers are equally likely to use Uber as taxi service in London. 3.1 Use appropriate research evaluation techniques Effectiveness of Project planning was developed by the researcher for implementing the current research project. The plan entailed the main steps of the project alongside milestones, objectives, review dates and resource allocation. This research plan was highly efficient in enabling the implementation of the research within the allocated time frame. One area where the research faced difficulty was in using ANOVA analysis method in data collation stage. The lack of knowledge and experience of the researcher in using ANOVA analysis method was a key obstacle in the smooth implementation of the research. Achievement of research objectives: Objective 1: To evaluate the factors affecting satisfaction of cab customers The primary objective of the current research was to evaluate the factors affecting satisfaction of cab customers. From the survey of taxi customers in London, the researcher was able to understand that convenience and accessibility were the most important factors that customers considered while selecting taxi service. From this it was inferred that convenience and accessibility of the cab service were the most important factors affecting satisfaction of UK cab customers. Objective 2: To assess the factors contributing to the competitive advantage of Uber in UK Taxi industry One of the other objectives of the research project was to assess the factors contributing to the competitive advantage of Uber in UK Taxi industry. With the help of the customer survey, the researcher evaluated the service quality dimensions of Uber. From this analysis it was understood that reliability, responsiveness and tangibility of service of Uber was rated highly by customers. From this it can be understood that Uber gains competitive advantage in UK taxi sector by offering reliable, responsive and tangible service. Objective 3: To analyse the impact of Ubers growth on mini cabs of UK The other objective of the research to analyse the impact of Ubers growth on mini cabs of UK. This was achieved by comparing the service quality of minicabs with that of Uber. From this comparison it was revealed that that reliability, responsiveness and tangibility of service of minicabs were inferior to that of Uber. This gap in service quality dimensions can be adjudged as the reason for the success of Uber in UK taxi market at the expense of minicabs. Objective 4: To provide suggestions to mini cabs of UK to remain competitive in UK Taxi industry The last objective of the research project was to provide suggestions to mini cabs of UK to remain competitive in UK Taxi industry. Form the research project it was understood that reliability, responsiveness and tangibility of service of minicabs were inferior to that of Uber. Hence it is recommended that minicabs seek improvement in reliability, responsiveness and tangibility elements of their service. Effectiveness of research methods: In the current research, survey method was used for collecting data from taxi customers in London. This data collection method was highly effective as it helped the researcher in collecting data from large number of customers with relative ease. As the data was collected from London this improves the validity of the research findings as London has a very diverse population. However, the research findings cannot be extrapolated across UK as the scope of the study was limited to London city. The research study is using both primary and secondary data. Primary data is obtained from the online survey and appropriate case study examples to interpret the results and Analysis. Secondary data has been used in Literature review .This section starts off by introducing you to four commonly used qualitative data collection methods. These collection methods and many others are also described and explained how to use them in evaluation. It then explains how you may go about involving participants: This is also known as sampling. The section ends with a discussion of a couple of approaches to qualitative data analysis. I will have to use some of these methods as part of your routine project monitoring activities, in a needs assessment or baseline or as part of an evaluation exercise. Quantitative and Qualitative data collection methods There are two ways of analysing qualitative data. One approach is to examine your findings with a pre-defined framework, which reflects your aims, objectives and interests. This approach is relatively easy and is closely aligned with policy and programmatic research which has pre-determined interests. This approach allows you to focus on particular answers and abandon the rest. I refer to this approach as framework analysis (Pope et al, 2000). The second approach takes a more exploratory perspective, encouraging me to consider and code all your data, allowing for new impressions to shape my interpretation in different and unexpected directions. I refer to this approach as thematic network analysis (Attride, 2001). Benefits of research results: The main benefit of the research results is that they outline the scope of competition between Uber and minicabs in UK taxi sector. This would help minicab service providers in understanding the areas where there is scope for improvement in their service. Difficulties faced in the research: One of the main difficulties faced in the current research was related to collecting data from taxi customers in London. The researcher faced difficulty in collecting data as the researcher lacked previous experience in collecting primary data through survey. 3.2 Interpretation and analysis of data 1. Gender Pie chart 1: Gender of the survey respondents Source: Created by the author Gender of the survey respondents is represented by the above pie diagram. From the above diagram, it is observed that relatively increased number of females (54.55%) constituted the participants of this survey program. 2. Rate the following factor in terms of their significance in your selecting a particular taxi serve (Scale of 1-5 where 1= Very high and 5= Very low) Bar chart 1: Ranking of factors that customers considers in selecting a taxi serve Source: Created by the author Analysing the significance of the various factors that a customer considers while adopting a taxi service, it is observed that convenience and accessibility were the mostly rated elements. The importance of safety element and pricing strategy were also identified from the customer responses. Thus it could be interpreted from this survey result that service efficiency, product attribute and pricing constitutes the main elements that influence the decision-making the process of the customers. This is in line with the literature study of Wallsten (2015) that explains the concept of Quality-value-loyalty chain. 3. Rate the following elements of service quality of Uber on a scale of 1-5 where 1 = Very good and 5= Very bad? Bar chart 2: Customer rating for the service attributes of Uber Source: Created by the author Responsiveness, tangibility and reliability were the highly rated characteristic features of Uber services. This is in line with the findings of Sundararajan (2014) and Isaac (2014) who identified that service excellence was the key element that provided an improved competitive advantage for Uber. However, it is also observed from the above pie diagram that Uber has received a negative customer response regarding its assurance. 4. Rate the following elements of service quality of minicabs of UK on a scale of 1-5 where 1 = Very good and 5= Very bad? Bar chart 3: Rating for the service quality of minicabs of UK Source: Created by the author A multitude of opinions was gathered from the customers regarding their rating for the service quality of minicabs. However analysing the above bar diagram it is apparent that majority of the customers has given comparatively a higher rating for the empathy element in the service quality of UK minicabs. 5. Rate the likelihood of you using the following services when you use taxi service next time on a scale of 1-5 (1= Very high and 5=Very low) Bar chart 4: Probability of selecting Uber and minicab services Source: Created by the author Analysing the probability of customers in selecting a taxi service, it is observed that majority of the participants opined that they prefer to opt Uber services. This signifies that Uber has achieved an improved recognition and competitive advantage compared to other minicab services of UK, which is in line with the reports of Isaac (2014) and Wallsten
Saturday, January 18, 2020
English â⬠comparing 1984 & The Handmaidââ¬â¢s Tale Essay
In The Handmaidââ¬â¢s Tale Margaret Atwood puts across the sense of mystery, things that were once there but are no more. She talks about ââ¬Ëthe pungent smell of sweat, shot through with the sweet smell of chewing gum and perfumeââ¬â¢ which came from the girls who once watched the basketball matches that were ââ¬Ëformally played thereââ¬â¢. In the first section of this book we get the feeling that the character is quite lost, lost in what once was and not in the here and now. She tells us about the dances that ââ¬Ëwould have been held thereââ¬â¢ and the lingering music that she could still hear very faintly. We get the feeling that this women has very little, no personal belongings, no wealth; nothing. The fact that the women in this building were not even allowed to exchange names tells the reader that this is some kind of prison, the women have no freedom they are constantly being watched by the ââ¬ËAngelsââ¬â¢ likewise in Nineteen Eighty-Four written by George Orwell there is a significant similarity between the ââ¬ËAngelsââ¬â¢ in The Handmaidââ¬â¢s Tale and the Posters in Nineteen Eighty-Four. The Angels watch over the women and in Nineteen Eighty-Four the poster which is described as a ââ¬Ëone of those pictures which are so contrived that the eyes follow you about when you move.ââ¬â¢ Watch over everyone who passes by it. Beneath it the caption read ââ¬ËBIG BROTHER IS WATCHING YOUââ¬â¢ giving off the impression that someone, somewhere is watching this middle aged man. The man described on the poster some might say could only be the description of Hitler; ââ¬Ëa man of about forty-five, with s heavy black moustache and ruggedly handsome featuresââ¬â¢ Winston also tells us that the posters were ââ¬Ëplastered everywhereââ¬â¢ also revealing, like The Handmaidââ¬â¢s Tale that nowhere is safe. Adding to this is the telescreen, which cannot be switched off again may be a sign that someone or something is always watching you, and that you are never alone. Both the Angels and the Posters in these books are very intimidating figures or ââ¬Ëobjects of fear.ââ¬â¢ The Angels did not look or talk to the women just stood with their backs to them to show domination. Correspondingly the ââ¬Ëenormous face, more than a metre wideââ¬â¢ plastered on the walls with the eyes that followed you when you move is also seen as a sign of domination. The two figures show signs of both aggression and great importance, the fact that the Angles will not talk or look at the women tells us that they are seen as more significant than them. In addition to this the fact that there are so many of these posters and the fixating look on the enormous face also shows great discomfort and stress.
Friday, January 10, 2020
How to Write a Term Paper for College - What Is It?
How to Write a Term Paper for College - What Is It? Life After How to Write a Term Paper for College The sort of sources used determines the standard of the term papers. If you wish to find high high quality research and thesis papers in time and for an affordable price, you should probably try out using EssaySupply.com. Term papers on the internet is the ideal alternative for folks who aren't prepared to have dead loss of their time. On our site you may find superior term papers for sale online. Developing strong writing skills needs a lot of practice. Anyway, dealing with a tough assignment can develop into a real problem whenever you have little understanding of the subject. While dealing with different subjects at the same time, students also work part-time, often more than 15 hours weekly, and also have to keep their social image and life instead of becoming an entire bookworm, something that's called as a nerd in the teen language. Some students aren't adept at writing and don't wish to have dead loss of time. Up in Arms About How to Write a Term Paper for College? A good deal of prior Term Paper is needed by the student to compose the Term Paper properly. Term paper writers have to possess several qualities so they can write the ideal term papers concerning quality. Writing Term Papers properly can't be carried out in one day, it takes a terrific period of time and effort to compose a proper Term Paper. Term papers are of various sorts. Unfortunately, there's no magic formula for making a thriving term paper. There are many measures that one must follow so he or she is able to write the ideal term papers. Even when you wrote a great college term paper employing the minimal sources, to be able to find a better grade you should cite at least two times more sources. Writing a term paper isn't easy as many individuals think. The debate may continue. however, it is true that business of custom term papers is prevailing and it's unlikely that it is going to ever fade away anytime soon. By way of example, sometimes you have to do just a little background research and reading before you may develop a research question. Whenever you have researched on a specific topic, you're expected to use a particular citation style. Like this students may offer brief breakdown of the topics in different sections. Don't be concerned about spelling or punctuation but make certain that you are in possession of a logical argument an d sufficient supporting evidence. You should back up all your suggestions and thoughts with strong and dependable evidence. Both are negative, which is a huge hint that you ought to use nor. It is extremely important to continue to keep your ideas and ideas organized. What Is So Fascinating About How to Write a Term Paper for College? There are a lot of online forums which students may join to examine their topic. In addition, the students are expected to compose papers that don't have any grammatical errors. After that students may create their very first draft following the outline. Before starting, make sure that you follow instructions provided to you. An individual ought to locate a hook or an angle. You must find the right set up for your house and get it installed. 1 thing to take into account in selecting a subject is to never choose one which is too common or too complicated. The Basic Facts of How to Write a Term Paper for College A research paper writer ought to have a well and crystal clear comprehension of the thesis and he must be an essential thinker. So you must always spell check your paper before submitting as it is quite significant part term paper writing and can't be neglected in any circumstance. If you believe that writing of a research paper is just about gathering relevant materials and copy-pasting then in a different document, you're mistaken. A research paper that concerns scientific issues is not only a free-style essay where you're able to tell readers whatever you desire. So, first of all, a college research paper has to be informative. To begin with, students must select a subject when writing term papers. Introduction Initially, they have to start with the introduction where you have to give the short summary of complete paper. Additionally, the students should pick a topic which is easy when writing a term paper. If you would like to write a superior term paper we would advice that you to obtain some reliable sources like well-known books and scientific articles. Our writers are the finest in the writing industry because we're very careful in our variety of workers. Furthermore, the writers in the business are needed to prepare draft when writing a term paper. They are supposed to have enough experience in helping students when writing a term paper. You must have language skills so you may easily write what you really need to, if you're a fluent writer your paper will express your language proficiency. Just make sure the graphics driver edition of your PC is updated to the newest version and also your system is joined to the web. Should you need expert writing help, don't hesitate to visit EssayPro.com. You may enhance your English writing, and you may do it easily.
Wednesday, January 1, 2020
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